Template:Second messenger system
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| cAMP System | Phosphoinositol system | Arachidonic acid system | cGMP System | Tyrosine kinase system | |
| First Messenger: Neurotransmitters (Receptor) |
Epinephrine (α2, β1, β2) Acetylcholine (M2) |
Epinephrine (α1) Acetylcholine (M1, M3) |
Histamine (Histamine receptor) | - | - |
| First Messenger: Hormones |
ACTH, ANP, CRH, CT, FSH, Glucagon, hCG, LH, MSH, PTH, TSH | AGT, GnRH, GHRH, Oxytocin, TRH | - | ANP, Nitric oxide | INS, IGF, PDGF |
| Signal Transducer | GPCR/Gs (β1, β2), Gi (α2, M2) | GPCR/Gq | Unknown G-protein | - | RTK |
| Primary effector | Adenylyl cyclase | Phospholipase C | Phospholipase A | guanylate cyclase | RasGEF (Grb2-Sos) |
| Second messenger | cAMP (cyclic adenosine monophosphate) | IP3; DAG; Ca2+ | Arachidonic acid | cGMP | Ras.GTP (Small G Protein) |
| Secondary effector | protein kinase A | PKC; CaM | 5-Lipoxygenase, 12-Lipoxygenase, cycloxygenase | protein kinase G | MAP3K (c-Raf) |
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